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   PID: hpt/lnx 1.9.0-cur 2019-01-08   
   TID: hpt/lnx 1.9.0-cur 2019-01-08   
    Taking good care of your teeth may be good for your brain    
    Poor dental health linked to decline in brain volume    
      
     Date:   
         July 5, 2023   
     Source:   
         American Academy of Neurology   
     Summary:   
         Taking good care of your teeth may be linked to better brain health,   
         according to a new study. The study found that gum disease and   
         tooth loss were linked to brain shrinkage in the hippocampus,   
         which plays a role in memory and Alzheimer's disease. The study   
         does not prove that gum disease or tooth loss causes Alzheimer's   
         disease; it only shows an association.   
      
      
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   FULL STORY   
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   Taking good care of your teeth may be linked to better brain health,   
   according to a study published in the July 5, 2023, online issue   
   of Neurology(R), the medical journal of the American Academy of   
   Neurology. The study found that gum disease and tooth loss were linked   
   to brain shrinkage in the hippocampus, which plays a role in memory and   
   Alzheimer's disease. The study does not prove that gum disease or tooth   
   loss causes Alzheimer's disease; it only shows an association.   
      
   "Tooth loss and gum disease, which is inflammation of the tissue around   
   the teeth that can cause shrinkage of the gums and loosening of the   
   teeth, are very common, so evaluating a potential link with dementia   
   is incredibly important," said study author Satoshi Yamaguchi, PhD,   
   DDS, of Tohoku University in Sendai, Japan. "Our study found that these   
   conditions may play a role in the health of the brain area that controls   
   thinking and memory, giving people another reason to take better care   
   of their teeth."  The study involved 172 people with an average age of   
   67 who did not have memory problems at the beginning of the study.   
      
   Participants had dental exams and took memory tests at the beginning of   
   the study. They also had brain scans to measure volume of the hippocampus   
   at the beginning of the study and again four years later.   
      
   For each participant, researchers counted the number of teeth and checked   
   for gum disease by looking at periodontal probing depth, a measurement   
   of the gum tissue. Healthy readings are from one to three millimeters.   
      
   Mild gum disease involves probing depths of three or four millimeters   
   in several areas, while severe gum disease involves probing depths of   
   five or six millimeters in several areas as well as more bone loss and   
   can cause teeth to become loose and eventually fall out.   
      
   Researchers found that the number of teeth and amount of gum disease   
   was linked to changes in the left hippocampus of the brain.   
      
   For people with mild gum disease having fewer teeth was associated with   
   a faster rate of brain shrinkage in the left hippocampus.   
      
   However, for people with severe gum disease having more teeth was   
   associated with a faster rate of brain shrinkage in the same area of   
   the brain.   
      
   After adjusting for age, researchers found that for people with mild gum   
   disease, the increase in the rate of brain shrinkage due to one less   
   tooth was equivalent to nearly one year of brain aging. Conversely,   
   for people with severe gum disease the increase in brain shrinkage due   
   to one more tooth was equivalent to 1.3 years of brain aging.   
      
   "These results highlight the importance of preserving the health of the   
   teeth and not just retaining the teeth," Yamaguchi said. "The findings   
   suggest that retaining teeth with severe gum disease is associated with   
   brain atrophy.   
      
   Controlling the progression of gum disease through regular dental visits   
   is crucial, and teeth with severe gum disease may need to be extracted   
   and replaced with appropriate prosthetic devices."  Yamaguchi said future   
   studies are needed with larger groups of people. Another limitation   
   of the study is that it was conducted in one region of Japan, so the   
   results may not be generalizable to other locations.   
      
   The study was supported by the Japanese Ministry of Education, Culture,   
   Sports, Science and Technology; Keio University; Japan Arteriosclerosis   
   Prevention Fund; Japanese Ministry of Health, Labor, and Welfare;   
   Teikyo University; Pfizer Japan; Bayer Yakuhin; Chugai Pharmaceutical;   
   Daiichi Sankyo; Astellas Pharma; Takeda Pharmaceutical; Health Care   
   Science Institute; Health Science Center; and Takeda Science Foundation.   
      
       * RELATED_TOPICS   
             o Health_&_Medicine   
                   # Dentistry # Healthy_Aging # Diseases_and_Conditions #   
                   Alzheimer's_Research   
             o Mind_&_Brain   
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                   # Dementia   
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   Journal Reference:   
      1. Satoshi Yamaguchi, Takahisa Murakami, Michihiro Satoh, Takamasa   
      Komiyama,   
         Takashi Ohi, Yoshitada Miyoshi, Kosei Endo, Takako Hiratsuka,   
         Azusa Hara, Yukako Tatsumi, Tomoko Totsune, Kei Asayama, Masahiro   
         Kikuya, Kyoko Nomura, Atsushi Hozawa, Hirohito Metoki, Yutaka Imai,   
         Makoto Watanabe, Takayoshi Ohkubo, Yoshinori Hattori. Associations   
         of Dental Health With the Progression of Hippocampal Atrophy in   
         Community-Dwelling Individuals: The Ohasama Study. Neurology,   
         2023; DOI: 10.1212/WNL.0000000000207579   
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   Link to news story:   
   https://www.sciencedaily.com/releases/2023/07/230705171101.htm   
      
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