MSGID: 1:317/3 6476cd7e   
   PID: hpt/lnx 1.9.0-cur 2019-01-08   
   TID: hpt/lnx 1.9.0-cur 2019-01-08   
    Obesity increases risk of mental disorders throughout life    
      
     Date:   
         May 30, 2023   
     Source:   
         Complexity Science Hub Vienna   
     Summary:   
         Being obese significantly increases the chances of also developing   
         mental disorders. This applies to all age groups, with women at   
         higher risk than men for most diseases.   
      
      
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   FULL STORY   
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   Being obese significantly increases the chances of also developing mental   
   disorders. This applies to all age groups, with women at higher risk than   
   men for most diseases, as a recent study of the Complexity Science Hub   
   and the Medical University of Vienna shows. The results were published   
   in the specialist journal Translational Psychiatry.   
      
   "We analyzed a population-wide national registry of inpatient   
   hospitalizations in Austria from 1997 to 2014 in order to determine the   
   relative risks of comorbidities in obesity and identify statistically   
   significant sex differences," explains Elma Dervic of the Complexity   
   Science Hub. Consequently, it became evident that an obesity diagnosis   
   significantly enhances the likelihood of a wide range of mental disorders   
   across all age groups - - including depression, nicotine addiction,   
   psychosis, anxiety, eating and personality disorders. "From a clinical   
   point of view, these results emphasise the need to raise awareness of   
   psychiatric diagnoses in obese patients and, if necessary, to consult   
   specialists at an early stage of diagnosis," says Michael Leutner of   
   the Medical University of Vienna.   
      
   FIRST DIAGNOSIS: OBESITY "In order to find out which illness typically   
   appeared prior and subsequently to the obesity diagnosis, we had to   
   develop a new method," explains Dervic.   
      
   This allowed the researchers to determine if there were trends and   
   typical patterns in disease occurrence.   
      
   In case of all co-diagnoses, with the exception of the psychosis spectrum,   
   obesity was in all likelihood the first diagnosis made prior to the   
   manifestation of a psychiatric diagnosis. "Until now, physicians often   
   considered psychopharmacological medications to cause the association   
   between mental disorders and obesity as well as diabetes. This may be   
   true for schizophrenia, where we see the opposite time order, but our   
   data does not support this for depression or other psychiatric diagnoses,"   
   explains Alexander Kautzky from Department of Psychiatry and Psychotherapy   
   of the Medical University Vienna. However, whether obesity directly   
   affects mental health or whether early stages of psychiatric disorders   
   are inadequately recognised is not yet known.   
      
   GREATER IMPACT IN WOMEN Surprisingly, the researchers found significant   
   gender differences for most disorders -- with women showing an increased   
   risk for all disorders except schizophrenia and nicotine addiction.   
      
   While 16.66% of obese men also suffer from nicotine abuse disorder, this   
   is only the case in up to 8.58% of obese women. The opposite is true   
   for depression. The rate of diagnosed depressive episodes was almost   
   three times higher in obese women (13.3% obese; 4.8% non-obese). Obese   
   men were twice as likely to be affected (6.61% obese; 3.21% non-obese).   
      
   COUNTERACT AT A YOUNG AGE At present, obesity is a highly prevalent   
   disease worldwide and affects more than 670 million people. The fact that   
   the disease promotes metabolic disorders and serious cardio-metabolic   
   complications (diabetes mellitus, arterial hypertension, and   
   dyslipidaemia) has already been extensively researched.   
      
   Since this study now also shows that obesity often precedes severe mental   
   disorders, the findings underscore its importance as a pleiotropic risk   
   factor for health problems of all kinds. This is primarily true for   
   young age groups, where the risk is most pronounced. For this reason,   
   thorough screening for mental health problems in obese patients is   
   urgently needed to facilitate prevention or ensure that appropriate   
   treatment can be given, so the researchers conclude.   
      
       * RELATED_TOPICS   
             o Health_&_Medicine   
                   # Obesity # Mental_Health_Research #   
                   Diseases_and_Conditions # Chronic_Illness   
             o Mind_&_Brain   
                   # Mental_Health # Psychiatry # Disorders_and_Syndromes   
                   # Depression   
       * RELATED_TERMS   
             o Estrogen o Misogyny o Arthritis o Personality_disorder o   
             Fertility o Psychopathology o Glaucoma o Premature_birth   
      
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   Story Source: Materials provided by Complexity_Science_Hub_Vienna. Note:   
   Content may be edited for style and length.   
      
      
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   Journal Reference:   
      1. Michael Leutner, Elma Dervic, Luise Bellach, Peter Klimek, Stefan   
         Thurner, Alexander Kautzky. Obesity as pleiotropic risk state   
         for metabolic and mental health throughout life. Translational   
         Psychiatry, 2023; 13 (1) DOI: 10.1038/s41398-023-02447-w   
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   Link to news story:   
   https://www.sciencedaily.com/releases/2023/05/230530125412.htm   
      
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