MSGID: 1:317/3 6406bdf4   
   PID: hpt/lnx 1.9.0-cur 2019-01-08   
   TID: hpt/lnx 1.9.0-cur 2019-01-08   
    Trouble falling asleep at bedtime or in the middle of the night? It   
   could impact your risk for developing dementia    
      
     Date:   
         March 6, 2023   
     Source:   
         Elsevier   
     Summary:   
         Adding to the growing body of evidence on sleep disturbances   
         and cognitive impairment, new research finds significant links   
         between three measures of sleep disturbance and the risk for   
         developing dementia over a 10-year period. The results associate   
         sleep-initiation insomnia (trouble falling asleep within 30   
         minutes) and sleep medication use with higher risk for developing   
         dementia. The investigators also found that people who reported   
         having sleep-maintenance insomnia (trouble falling back to sleep   
         after waking) were less likely to develop dementia over the course   
         of the study.   
      
      
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   FULL STORY   
   ==========================================================================   
   Adding to the growing body of evidence on sleep disturbances and cognitive   
   impairment, new research finds significant links between three measures   
   of sleep disturbance and the risk for developing dementia over a 10-year   
   period.   
      
   The results, reported in the American Journal of Preventive Medicine,   
   published by Elsevier, associate sleep-initiation insomnia (trouble   
   falling asleep within 30 minutes) and sleep medication use with higher   
   risk for developing dementia.   
      
   The investigators also found that people who reported having   
   sleep-maintenance insomnia (trouble falling back to sleep after waking)   
   were less likely to develop dementia over the course of the study.   
      
      
   ==========================================================================   
   "We expected sleep-initiation insomnia and sleep medication usage to   
   increase dementia risk, but we were surprised to find sleep-maintenance   
   insomnia decreased dementia risk," explained lead investigator Roger Wong,   
   PhD, MPH, MSW, an Assistant Professor in the Department of Public Health   
   and Preventive Medicine, SUNY Upstate Medical University, Syracuse, NY,   
   USA. "The motivation behind this research was prompted on a personal   
   level. My father has been experiencing chronic sleep disturbances since   
   the COVID-19 pandemic began, and I was concerned how this would affect   
   his cognition in the future. After reading the existing literature, I   
   was surprised to see mixed findings on the sleep-dementia relationship,   
   so I decided to investigate this topic."  This research is novel because   
   it is the first to examine how long-term sleep disturbance measures are   
   associated with dementia risk using a nationally representative US older   
   adult sample. Previous research has associated REM sleep behavior,   
   sleep deprivation (less than five hours of sleep), and the use of   
   short-acting benzodiazepines with cognitive decline. Their results for   
   sleep-maintenance insomnia support other recent studies using smaller,   
   separate data samples.   
      
   This study used 10 annual waves (2011?2020) of prospective data from the   
   National Health and Aging Trends Study (NHATS), a longitudinal panel study   
   that surveys a nationally representative sample of Medicare beneficiaries   
   aged 65 years and older within the USA. This study included only people   
   who were dementia-free at baseline in 2011.   
      
   There is no cure for dementia and recent pharmaceutical approaches to   
   treat dementia have had limited success, pointing to the importance of   
   preventive approaches to dementia. "By focusing on the variations in sleep   
   disturbances, our findings can help to inform lifestyle changes that can   
   reduce dementia risk," explained co-investigator Margaret Anne Lovier,   
   MPH, Department of Public Health and Preventive Medicine, SUNY Upstate   
   Medical University, Syracuse, NY, USA.   
      
   While the mechanism for decreased dementia risk among those with sleep-   
   maintenance insomnia is still unknown, the investigators theorize that   
   greater engagement in activities that preserve or increase cognitive   
   reserve may thereby decrease dementia risk.   
      
   Recent evidence indicates there is a higher prevalence of sleep   
   disturbances among older adults than among other age groups. This could   
   be attributed to a variety of factors including anxiety about the COVID-19   
   pandemic or warmer nights as a consequence of climate change.   
      
   "Older adults are losing sleep over a wide variety of concerns. More   
   research is needed to better understand its causes and manifestations and   
   limit the long-term consequences," added Dr. Wong. "Our findings highlight   
   the importance of considering sleep disturbance history when assessing   
   the dementia risk profile for older adults. Future research is needed to   
   examine other sleep disturbance measures using a national longitudinal   
   sample, whether these sleep- dementia findings hold true for specific   
   dementia subtypes, and how certain sociodemographic characteristics may   
   interact with sleep disturbances to influence dementia risk."   
       * RELATED_TOPICS   
             o Health_&_Medicine   
                   # Sleep_Disorder_Research # Insomnia_Research #   
                   Alzheimer's_Research # Healthy_Aging   
             o Mind_&_Brain   
                   # Sleep_Disorders # Insomnia # Obstructive_Sleep_Apnea   
                   # Dementia   
       * RELATED_TERMS   
             o Delayed_sleep_phase_syndrome o Sleep_deprivation   
             o Sleep_disorder o Insomnia o Night_terror o   
             Circadian_rhythm_sleep_disorder o Sleep_apnea o   
             Obstructive_sleep_apnea   
      
   ==========================================================================   
   Story Source: Materials provided by Elsevier. Note: Content may be edited   
   for style and length.   
      
      
   ==========================================================================   
   Journal Reference:   
      1. Roger Wong, Margaret Anne Lovier. Sleep Disturbances and Dementia   
      Risk in   
         Older Adults: Findings From 10 Years of National U.S. Prospective   
         Data.   
      
         American Journal of Preventive Medicine, 2023; DOI: 10.1016/   
         j.amepre.2023.01.008   
   ==========================================================================   
      
   Link to news story:   
   https://www.sciencedaily.com/releases/2023/03/230306143443.htm   
      
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