MSGID: 1:317/3 63f05474   
   PID: hpt/lnx 1.9.0-cur 2019-01-08   
   TID: hpt/lnx 1.9.0-cur 2019-01-08   
    New antioxidants found in beef, chicken, and pork    
    Establishment of a highly sensitive detection method for imidazole   
   dipeptide oxidation derivatives    
      
     Date:   
         February 17, 2023   
     Source:   
         Osaka Metropolitan University   
     Summary:   
         Scientists found that 2-oxo-imidazole-containing dipeptides   
         (2-oxo-IDPs) exhibit very high antioxidant activity. Furthermore,   
         they established a method to selectively and sensitively detect   
         very small amounts of 2-oxo- IDPs and revealed for the first time   
         that several types of 2-oxo-IDPs are contained in meat, including   
         beef, pork, and chicken.   
      
      
         Facebook Twitter Pinterest LinkedIN Email   
   FULL STORY   
   ==========================================================================   
   Imidazole dipeptides (IDPs), which are abundant in meat and fish,   
   are substances produced in the bodies of various animals, including   
   humans, and have been reported to be effective in relieving fatigue and   
   preventing dementia. However, the physiological mechanism by which IDPs   
   exhibit these activities had not been determined previously.   
      
      
   ==========================================================================   
   A research team, led by Professor Hideshi Ihara from the Osaka   
   Metropolitan University Graduate School of Science, was the first to   
   discover 2-oxo- imidazole-containing dipeptides (2-oxo-IDPs) -- which   
   have one more oxygen atom than normal IDPs -- and found that they are   
   the most common variety of IDPs derivatives in the body. The researchers   
   also found that they have remarkably high antioxidant activity.   
      
   In their study, the researchers established a method for selective   
   and highly sensitive detection of five types of 2-oxo-IDPs using mass   
   spectrometry, which enables quantitative detection of trace 2-oxo-IDPs   
   in living organisms. Using this method, they revealed for the first   
   time that beef, pork, chicken, and other meats contain antioxidants,   
   not only IDPs but a variety of different 2- oxo-IDPs. Their findings   
   were published in Antioxidants.   
      
   "We hope that this research method, which enables advanced analysis   
   of 2-oxo- IDPs, will be applied not only to basic biology but also to   
   medicine, agriculture, and pharmacy, where it will help improve peoples'   
   health and prevent diseases," concluded Professor Ihara.   
      
       * RELATED_TOPICS   
             o Health_&_Medicine   
                   # Pain_Control # Medical_Topics # Vegetarian #   
                   Diseases_and_Conditions   
             o Plants_&_Animals   
                   # Cows,_Sheep,_Pigs # Soil_Types # Biology # Wild_Animals   
       * RELATED_TERMS   
             o Hereford_(cattle) o Meat_analogue o Beef o Food_groups o   
             Glycogen o Pig o Health_benefits_of_tea o Mustang_horse   
      
   ==========================================================================   
   Story Source: Materials provided by Osaka_Metropolitan_University. Note:   
   Content may be edited for style and length.   
      
      
   ==========================================================================   
   Journal Reference:   
      1. Somei Komae, Shingo Kasamatsu, Koji Uchida, Hideshi   
      Ihara. Quantitative   
         Determination of 2-Oxo-Imidazole-Containing Dipeptides   
         by High- Performance Liquid Chromatography/Tandem Mass   
         Spectrometry. Antioxidants, 2022; 11 (12): 2401 DOI:   
         10.3390/antiox11122401   
   ==========================================================================   
      
   Link to news story:   
   https://www.sciencedaily.com/releases/2023/02/230217081439.htm   
      
   --- up 50 weeks, 4 days, 10 hours, 50 minutes   
    * Origin: -=> Castle Rock BBS <=- Now Husky HPT Powered! (1:317/3)   
   SEEN-BY: 15/0 106/201 114/705 123/120 153/7715 226/30 227/114 229/110   
   SEEN-BY: 229/111 112 113 114 307 317 400 426 428 470 664 700 292/854   
   SEEN-BY: 298/25 305/3 317/3 320/219 396/45   
   PATH: 317/3 229/426