MSGID: 1:317/3 627201ae   
   PID: hpt/lnx 1.9.0-cur 2019-01-08   
   TID: hpt/lnx 1.9.0-cur 2019-01-08   
    Endocrine-disrupting chemicals may impair bone health in male teens   
      
      
     Date:   
         May 3, 2022   
     Source:   
         The Endocrine Society   
     Summary:   
         Per- and polyfluoroalkyl substances (PFAS) and phthalates (two   
         types of endocrine-disrupting chemicals) may be associated with   
         lower bone mineral density in male teens, according to a new study.   
      
      
      
   FULL STORY   
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   Per- and polyfluoroalkyl substances (PFAS) and phthalates (two types   
   of endocrine-disrupting chemicals) may be associated with lower bone   
   mineral density in male teens, according to a new study published in   
   the Endocrine Society's Journal of Clinical Endocrinology and Metabolism.   
      
      
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   Endocrine-disrupting chemicals are chemicals or mixtures of chemicals that   
   interfere with the way the body's hormones work. Per- and polyfluoroalkyl   
   substances (PFAS) are synthetic chemicals used in nonstick cookware,   
   clothing and food packaging, and are increasingly being found in   
   U.S. water supplies.   
      
   Phthalates are used in personal care products, food processing and   
   children's toys.   
      
   "Adolescence is an important time when our bodies build up bone. Almost   
   all U.S. children and adolescents are exposed to PFAS and phthalates, but   
   few studies have looked at how these chemicals could be impacting our bone   
   health," said Abby F. Fleisch, M.D., M.P.H., of the Maine Medical Center   
   Research Institute and Maine Medical Center in Portland, Maine. "Our   
   research found an association between certain PFAS and phthalates and   
   reduced bone mineral density in adolescent males. Because bone accrual   
   primarily occurs during adolescence, if replicated, this finding may have   
   implications for lifelong bone health."  The researchers leveraged urine   
   and blood samples from 453 boys and 395 girls from the National Health   
   and Nutrition Examination Survey (NHANES) and found higher levels of   
   PFAS and phthalates may be associated with lower bone mineral density in   
   adolescent males. The researchers did not find the same effect in girls.   
      
   Other authors of this study include: Jenny L. Carwile, Shravanthi   
   M. Seshasayee and Clifford J. Rosen of the Maine Medical Center Research   
   Institute; Katherine A. Ahrens of the University of Southern Maine in   
   Portland, Maine; Russ Hauser of the Harvard T. H. Chan School of Public   
   Health in Boston, Mass.; Jeffrey B.   
      
   Driban of the Tufts Medical Center in Boston, Mass.; and Catherine   
   M. Gordon of the Texas Children's Hospital and Baylor College of Medicine   
   in Houston, Texas.   
      
   The study received funding from the National Institute of Environmental   
   Health Sciences.   
      
      
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   Story Source: Materials provided by The_Endocrine_Society. Note: Content   
   may be edited for style and length.   
      
      
   ==========================================================================   
   Journal Reference:   
      1. Jenny L Carwile et al. Serum PFAS and Urinary Phthalate Biomarker   
         Concentrations and Bone Mineral Density in 12-19 Year Olds:   
         2011-2016 NHANES. JCEM, 2022 DOI: 10.1210/clinem/dgac228   
   ==========================================================================   
      
   Link to news story:   
   https://www.sciencedaily.com/releases/2022/05/220503091558.htm   
      
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